Grape Seed Extract Inhibits Growth of Colorectal Tumors
According to a study funded by the National Cancer Institute, the chemicals founds in grape seeds were able to significantly inhibit the growth of colorectal tumors in both cell cultures and in mice.
The said study revealed a 44 percent reduction of advanced colorectal tumors in the animals, and also revealed, for the first time, the molecular mechanism by which grape seed extract works to inhibit cancer growth.
The authors found that it (grape seed extract) increases availability of a critical protein, Cip1/p21, in tumors that effectively freezes the cell cycle, and often pushes a cancer cell to self destruct.
According to Rajesh Agarwal, Ph.D., professor in the Department of Pharmaceutical Sciences at the University of Colorado Health Sciences Center in Denver:
“With these results, we are not suggesting that people run out and buy and use grape seed extract.
That could be dangerous since so little is known about doses and side effects.
The value of this preclinical study is that it shows grape seed extract can attack cancer, and how it works, but much more investigation will be needed before these chemicals can be tested as a human cancer treatment and preventive.”
The study is published in the October 18 issue of Clinical Cancer Research.
Find more details from the full report at the American Association for Cancer Research.
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POSTED IN: on anti-cancer ingredients, on colon cancer
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