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Cancer Commentary - Caring About Cancer

Natural Selection and Cancer

by Gayla McCord on December 16th, 2006

From So Simple a Beginning: Darwin's Four Great Books (Voyage of the Beagle, The Origin of Species, The Descent of Man, The Expression of Emotions in Man and Animals)Science writer Carl Zimmer, who also writes The Loom, has a fantastic piece in the January 2007 issue of Scientific American (not yet online for nonsubscribers) discussing natural selection and its role in cancer development.

Here’s the overview on cancer evolution:

  • Natural selection has only a limited ability to prevent cancer. It has provided some defenses, but these tend to delay the disease until late in life rather than eliminating it entirely.
  • In addition, evolutionary forces have apparently favored some genes that can contribute to cancer’s development or aggressiveness.
  • An understanding of cancer’s evolutionary history.and how individual tumors evolve in the body.could suggest fresh angles of attack on the disorder.

PS The picture is of a collection of Charles Darwin’s four great books: Voyage of the Beagle, The Origin of Species, The Descent of Man, The Expression of Emotions in Man and Animals.

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