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Cancer Commentary - Caring About Cancer

Obesity and Diabetes Gene, Found Player in Breast Cancer

by Gloria Gamat on February 8th, 2007

Published in Nature Genetics is the discovery of the role played by a gene associated with the propagation of breast cancer (in 2 out of 5 affected women) by Michel L. Tremblay and his team at the Cancer Centre at McGill University.

The gene, identified as PTP1b, already known for its role in diabetes and obesity, has been found to be a player in the promotion of the proliferation and metastasis of cancer tumors.

An article published by the same group of researchers in Science in 1999 showed that suppressing the enzyme produced by the gene PTP1b made it possible to cure type II diabetes and obesity. A large number of pharmaceutical companies have since developed new inhibitors used in treatments for these diseases.

Read the full report at McGill University.

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POSTED IN: Breast cancer

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