CDX2: Protein Promoting Leukemia
A protein known as CDX2 is inappropriately expressed in the leukemic cell of patients with acute myeloid leukemia (AML), according to a study from Harvard Medical School appearing in the April print issue of the Journal of Clinical Investigation.
…gene encoding CDX2 is expressed in 90% of the patients with AML that they analyzed. Moreover, reducing the amount of CDX2 in human AML cell lines decreased their ability to proliferate, indicating that CDX2 has a causal role in the pathogenesis of AML.
CDX2 might provide new targets for the treatment of acute myeloid leukemia.
Find more details from the full report.
Tags: acute-myeloid-leukemia, protein-CDX2Related Stories
POSTED IN: on blood cancer
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