Radio-labelled Antibody PET Imaging Identifies Kidney Cancer for Surgery
Cell renal carcinoma is the most common and aggressive type of renal tumor or kidney cancer.
Imaging with Positron Emission Tomography (PET) using a radiolabeled monoclonal antibody G250 (originally developed as a potential therapeutic agent) can accurately identify cell renal carcinoma that needs surgery.
This was based on findings of a new study done by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).
…15 out of 16 clear cell renal carcinomas were correctly identified using G250 PET, resulting in a sensitivity of 94 percent. All 9 patients with non-clear cell renal masses were negative on the PET scan — which is highly predictive of a less aggressive cancer — resulting in a specificity of 100 percent.
This promising result suggests that G250 PET (being sensitive and specific) can be utilized in identification of management strategies for clinically localized renal masses and as an alternative to biopsy for distinguishing renal lesions.
Study results will be published in the April 2007 issue of The Lancet Oncology (online March 6/7).
Read the full report.
Tags: kidney-cancer, PET-ImagingRelated Stories
POSTED IN: on cancer diagnostics, on kidney cancer
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