Folic Acid Supplementation Do Not Reduce Risk of Colorectal Tumors
While folic acid supplementation may reduce the risk of stroke, it does not reduce the risk of colorectal cancers (but could even possible increase the risk of some types of colorectal cancers) even though previous studies have suggested that folate supplementation may help prevent colorectal cancers.
[Err, folic acid is synthetic while folate is the natural form!]
This new finding has been the result of a trial conducted at nine clinical centers in the U.S. and Canada between July 1994 and October 2004 that included 1,021 men and women with a recent history of colorectal adenomas but no previous large intestine cancerous tumor.
According to the authors of the study, led by Bernard F. Cole, Ph.D., of Dartmouth Medical School (Hanover, N.H.) :
“In conclusion, our study indicates that folate, when administered as folic acid for up to 6 years, does not decrease the risk of adenoma formation in the large intestine among individuals with previously removed adenomas.
The evidence for an increased risk of adenomas is equivocal and requires further research. In view of the fortification of the U.S. food supply with folate, and some suggestions that folate could conceivably increase the risk of neoplasia even outside the colorectum, this line of investigation should have a high priority.”
Results have been reported in the June 6 issue of JAMA.
Find more details from the full report.
Tags: colorectal-cancer, folate, folic-acidRelated Stories
POSTED IN: Colon cancer, ~ Anti-cancer treatments ~
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