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Cancer Commentary - Caring About Cancer

July 19th, 2008

ImClone’s Erbitux: Approved in Japan For Colorectal Cancer Use

ImClone Systems, Inc.’s advanced colorectal cancer drug has now received regulatory approval in Japan.
ERBITUX(R) (cetuximab) has received marketing authorization in Japan for use in treating patients with advanced or metastatic colorectal cancer (mCRC).
Specifically, this approval allows for the use of ERBITUX to treat patients with epidermal growth factor receptor (EGFR)-positive, curatively unresectable (inoperable), advanced or […]

By Gloria Gamat -- 0 comments

June 19th, 2008

Flavonols Against Colorectal Cancer

Okay…here goes another news on flavonols from tea, onions, beans and apples. As suggested by findings of a new U.S. study, increased intake of such flavonols may reduce risk of colorectal cancer by as much as 76 percent.
Findings were published in this month’s Cancer Epidemiology Biomarkers & Prevention:
Analysis of data from a randomised dietary intervention […]

By Gloria Gamat -- 1 comment

March 27th, 2008

March 2008: National Colorectal Cancer Awareness Month

Colorectal cancer - sometimes called (large) bowel cancer or simply colon cancer - seems to be in the air this week. Now that the month of March is nearly over and before I totally forget, let me quickly mention that this month is National Colorectal Cancer Awareness Month.
According to CDC :
March is National Colorectal Cancer […]

By Gloria Gamat -- 0 comments

March 14th, 2008

Allergic Reaction To Cancer Drug Cetuximab (Erbitux), Found

An allergic reaction to the cancer drug cetuximab has been found.
Sometimes the reaction includes anaphylaxis, a life-threatening condition characterized by a drop in blood pressure, fainting, difficulty breathing, and wheezing.
Now researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have discovered that specific pre-existing antibodies […]

By Gloria Gamat -- 2 comments

January 30th, 2008

An Aspirin a Day Keeps Colorectal Cancer Away

Before it was an aspirin a day keeps the heart doctor away.
Now, according to a study published in Gastroenterology (the official journal of the American Gastroenterological Association (AGA) Institute), the use of regular, long-term aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk associated with colorectal cancer.
According to Andrew T. Chan, MD, MPH, Massachusetts General […]

By Gloria Gamat -- 0 comments

November 25th, 2007

Vitamin B Deficiency May Promote Colon Cancer

According to a new study in mice (led by Zhenhua Liu from Tufts University), moderate deficiency of folate, riboflavin, and vitamins B6 and B12 together may promote the risk of DNA damage and increase the risk of colorectal cancers.
The researchers, led by Zhenhua Liu from Tufts University, studied the Wnt pathway - a cellular signalling […]

By Gloria Gamat -- 3 comments

November 7th, 2007

Molecular Analogues of Curry Better Fight Colorectal Cancer

Curcumin has long been known for its anti-cancer properties.
Curcumin is the yellowish component of turmeric that gives curry its flavor.

I am not a fan of dishes that use curry. However, if cooked just right I may actually like it. My mother’s version of chicken curry (not too pungent but not bland either) is one of […]

By Gloria Gamat -- 1 comment

August 13th, 2007

High-Choline Diet Can Increase Risk of Colorectal Polyps

Dietary sources of the nutrient choline are red meat, eggs, poultry and dairy product.
Choline is involved in the biochemical process known as one-carbon metabolism.
As opposed to expected, diets high in choline have been found associated with an increased risk of some colorectal polyps – which can (but do not always) lead to colorectal cancer.
Such were […]

By Gloria Gamat -- 0 comments

August 2nd, 2007

Two Glasses of Wine Daily and Risk of Colon Cancer

According to a study by Cancer Research UK, drinking two large glasses of wine a day increases the risk of getting bowel cancer by a quarter while even one large glass can increase the risk by 10 percent.
The warnings will come as a huge worry to millions of middle class Britons who enjoy a […]

By Gloria Gamat -- 2 comments

July 3rd, 2007

Vitamin B6 and Colorectal Cancer

Low intake of Vitamin B6 may increase a man’s risk of colorectal cancer by 31%, says the Japan Public Health Center-based Prospective Study, published in this month’s issue of Journal of Nutrition.
According to lead author Junko Ishihara from Japan’s National Cancer Center in collaboration with researchers from Gunma University Graduate School of Medicine:
Our results support […]

By Gloria Gamat -- 1 comment