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Cancer Commentary - Caring About Cancer

December 12th, 2007

More Good News From Gleevec

The targeted cancer pill – Gleevec - has been approved for the treatment of gastrointestinal stromal tumors, pediatric CML, as well as five additional rare cancers.
While it has been reported to have saved more than 100,000 lives, Gleevec is now saving more children with a dire leukemia (Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) ), […]

By Gloria Gamat -- 1 comment

December 5th, 2007

WBZ-4: Re-engineered Gleevec™, Reduces Cardio Risks

The powerful anti-cancer drug imatinib (Gleevec™) has been re-engineered by researchers at Rice University and the University of Texas M. D. Anderson Cancer Center.
Developed by Novartis Pharmaceuticals, Gleevec is approved by the U.S. Food and Drug Administration for the treatment of chronic myeloid leukemia (CML), Philadelphia-chromosome positive acute lymphoblastic leukemia and GIST.
The drug targets two […]

By Gloria Gamat -- 1 comment

October 8th, 2007

Imatinib Can Totally Cure Chronic Myeloid Leukemia

The drug imatinib has been found to drive cancer into remission in people with chronic myeloid leukemia (CML). But CML often returns when treatment is stopped.
Now, according to a new research by a team from UC-Irvine, imatinib could cure CML under certain circumstances if it is taken over a long enough period of time.
According to […]

By Gloria Gamat -- 0 comments

April 18th, 2007

Cancer Drug Gleevec® Decreases Recurrence in Primary Gastrointestinal Stromal Tumor (GIST) Patients

Primary gastrointestinal stromal tumor (GIST) is a type of tumor often found in the stomach or small intestine.
Preliminary data of a large, randomized, placebo-controlled clinical trial which tested imatinib mesylate (Gleevec ®) in patients with primary gastrointestinal stromal tumor (GIST) following complete removal of their tumor were found to be significantly less likely to have […]

By Gloria Gamat -- 1 comment

September 22nd, 2006

Jefferson Scientists Found Way that Might Sidestep Gleevec Resistance

Once more, the miracle drug Gleevec, takes center stage.
The leukemia drug Gleevec, though hugely successful has some downsides too: heart failure in a few patients as shown in previous studies and now, drug resistance continues to be a problem.
Now, Kimmel Cancer Center at Thomas Jefferson University may have discovered a way to sidestep such […]

By Gloria Gamat -- 0 comments

August 1st, 2006

‘Miracle’ Cancer Drug Gleevec May be Harmful to the Heart

The “miracle” cancer drug Gleevec and other similarly based drugs (tyrosine kinase inhibitors) could be harmful to the heart, according to a research at the Center for Translational Medicine at Jefferson Medical College in Philadelphia.
A team of scientists led by Thomas Force, M.D., James C. Wilson Professor of Medicine at Jefferson Medical College of Thomas […]

By Gloria Gamat -- 1 comment